Amyra Dastur
Amyra Dastur, a Parsi mumbai based model made her tamil movie debut in K V Anand's Dhanush starrer Anegan.
Nikki Galrani
Nikki is a Sindhi girl from Bangalore and the younger sister of Sanjjanaa Reddy. She had her first tamil release in a horror comedy Darling though her first signed movie was Yagavarayinum Naa Kaakka.She had already won the Filmfare Award for Best Female Debut–South for her performance in her debut Malayalam movie 1983.She was also the Top Star-Female (Malayalam) 2014 in our list for multiple commercial success.
Preethi Christina Paul
Preethi,a malayalee was one of the female leads in Serndhu Polama,a tamil film shot primarily in New Zealand.
Neha Ratnakaran
Neha Ratnakaran,a malayalee model and the 1st runner up in Miss Malabar beauty paegant 2013, made her tamil movie debut in Ivanuku Thanilla Gandham.
Sushma Raj
Sushma Raj,a telugu-kannada actress made her tamil debut in the romantic comedy, India Pakistan as a lawyer.
Savitri(Sulagna)

Sulagna Panigrahi, aka Savitri, a bollywood actress from Orissa,who had also previously acted in hindi television serials made her tamil debut in S J Suryah starrer Isai.She had also done her own costume in her Marathi film
Deepa Sannidhi
Deepa Sannidhi aka Rahasya,a Kannada actress debuted in tamil with the same role that she did in Kannada film Lucia, in its tamil remake Enakkul Oruvan.She has also done modelling and learned jewellery designing.
Aishwarya Dutta
Aishwarya Dutta made her acting debut with Ramprakash Rayappa's Tamizhuku En Ondrai Azhuthavum.
Keerthy Suresh
Keerthy Suresh a malayalam actress and a graduate in fashion designing had her first tamil film in Idhu Enna Mayam.She is the younger daughter of ace malayalam movie producer Suresh and yester-year actress Menaka .
Kavya Shetty
Kavya Shetty,‘Miss Photogenic’ at the 2011 Femina Miss India beauty pageant and a finalist at the Ford Super Model of the World – India,2011 had her debut film in Kannada.She had signed for other tamil movies but her first release in tamil was Idhu Enna Mayam.
Jai Quehani
Jai Quehani a graduate in Film Technology made her debut in Charles Shafiq Karthika.
Neha Hinge
Neha was the Femina Miss India International, 2010 and Miss Fresh Face, Miss Professional and Miss Bollywood Diva in the same pageant .She was the female lead in the bollywood film launching actress Rati Agnihotri's son.She made her tamil debut in Sagapatham,the launchpad of Shanmugapandian, the son of actor-politician Vijayakanth.She is from Madhya Pradesh.
Subhra Aiyappa

Shubra Aiyappa a bangalore based model and telugu actress made her tamil debut in Sagaptham,the launchpad of Shanmugapandian,the son of veteran actor-politician Vijayakanth.
Sakshi Agarwal
Sakshi Agarwal a Kannada actress did her first tamil movie Yoogan,a horror flick.
Kanika Tiwari
Kanika Tiwari who did the role of Hrithik Roshan's sister in the movie Agneepath made her tamil movie debut with the horror comedy Aavikumar.